Arecoline inhibits epithelial cell viability by upregulating the apoptosis pathway: implication for oral submucous fibrosis.

@article{Li2014ArecolineIE,
  title={Arecoline inhibits epithelial cell viability by upregulating the apoptosis pathway: implication for oral submucous fibrosis.},
  author={Ming Li and Feng Gao and Zhong-Su Zhou and Hui-Ming Zhang and Rui Zhang and Ying-fang Wu and Ming-Hai Bai and Ji-Jia Li and Shi-Rong Lin and Jie-ying Peng},
  journal={Oncology reports},
  year={2014},
  volume={31 5},
  pages={2422-8}
}
Oral submucous fibrosis (OSF) is a chronic inflammatory disease characterized by the accumulation of excess collagen, and areca nut chewing has been proposed as a significant etiological factor for disease manifestation. However, the underlying molecular mechanisms regarding areca nut chewing-induced OSF are only partially understood. Herein, we reported… CONTINUE READING