Are we dependent upon coffee and caffeine? A review on human and animal data

@article{Nehlig1999AreWD,
  title={Are we dependent upon coffee and caffeine? A review on human and animal data},
  author={Astrid Nehlig},
  journal={Neuroscience & Biobehavioral Reviews},
  year={1999},
  volume={23},
  pages={563-576}
}
Caffeine is the most widely used psychoactive substance and has been considered occasionally as a drug of abuse. The present paper reviews available data on caffeine dependence, tolerance, reinforcement and withdrawal. After sudden caffeine cessation, withdrawal symptoms develop in a small portion of the population but are moderate and transient. Tolerance to caffeine-induced stimulation of locomotor activity has been shown in animals. In humans, tolerance to some subjective effects of caffeine… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 164 CITATIONS

Caffeine and cognitive control : behavioral and electrophysiological studies

VIEW 9 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Craving espresso: the dialetics in classifying caffeine as an abuse drug

  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 2018
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The Safety of Ingested Caffeine: A Comprehensive Review

  • Front. Psychiatry
  • 2017
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Caffeine use in children: What we know, what we have left to learn, and why we should worry

  • Neuroscience & Biobehavioral Reviews
  • 2009
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Plant alkaloids as drug leads for Alzheimer's disease

  • Neurochemistry International
  • 2015
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1970
2018

CITATION STATISTICS

  • 19 Highly Influenced Citations

  • Averaged 13 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 194 REFERENCES

The consumption of coffee. In: Garattini S, editor. Caffeine, coffee and health

A D’Amicis, R. Viani
  • 1993
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Caffeine consumption

R. Viani
  • Proceedings of the Caffeine Workshop, Thai FDA and ILSI Bangkok, Thailand,
  • 1996
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

The composition of coffee

VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…