Are thiopurines always contraindicated after thiopurine-induced pancreatitis in inflammatory bowel disease?

@article{Ledder2013AreTA,
  title={Are thiopurines always contraindicated after thiopurine-induced pancreatitis in inflammatory bowel disease?},
  author={Oren D Ledder and Daniel A Lemberg and Chee Yee Ooi and Andrew S Day},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2013},
  volume={57 5},
  pages={583-6}
}
BACKGROUND AND AIMS Thiopurine use in inflammatory bowel disease (IBD) is well established for maintenance of disease remission. Approximately 3% of patients with IBD develop thiopurine-induced pancreatitis (TIP) as an idiosyncratic reaction. Patients diagnosed as having TIP are largely considered not to be candidates for future use of this drug. We hypothesize that previous TIP is not an absolute contraindication to retrialing a different thiopurine. METHODS This case series is a… CONTINUE READING
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