Are there unique autoantigens triggering autoimmune diseases?

  title={Are there unique autoantigens triggering autoimmune diseases?},
  author={J. F. Bach and Sophie Koutouzov and Peter van Endert},
  journal={Immunological reviews},
Using three reference disease models--insulin-dependent diabetes mellitus (IDDM) as a prototype of T-cell mediated organ-specific autoimmune disease, myasthenia gravis (MG) as a prototype of autoantibody-mediated organ-specific autoimmune disease and systemic lupus erythematosus (SLE) as a prototype of non-organ-specific autoimmune disease--we have reached several conclusions: 1) All three diseases are associated with the presence of multiple autoantibodies and/or autoreactive T cells that… CONTINUE READING
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