Are there time-period-related differences in the prophylactic effects of Bacille Calmette-Guerin intravesical instillation therapy in Japan?

@article{Okamura2012AreTT,
  title={Are there time-period-related differences in the prophylactic effects of Bacille Calmette-Guerin intravesical instillation therapy in Japan?},
  author={Takehiko Okamura and R Ando and Hidetoshi Akita and Yoshihiro Hashimoto and Yutaka Iwase and Taku Naiki and Noriyasu Kawai and Keiichi Tozawa and Kenjiro Kohri},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2012},
  volume={13 9},
  pages={4357-61}
}
OBJECTIVE The guidelines on indications for prophylactic use of Bacille Calmette-Guerin (BCG) against non- muscle-invasive bladder cancer (NMIBC) have changed over the years. In order to assess the impact on outcome, the present retrospective comparison of BCG efficacy by time period with Japanese patients was conducted. PATIENTS AND METHODS A total of 146 cases of NMIBC treated with BCG since February 1985 were retrospectively evaluated. All patients received 80 mg of BCG (Tokyo 172 strain… CONTINUE READING

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