Are therapeutic diets an emerging additional choice in autism spectrum disorder management?

@article{Gogou2018AreTD,
  title={Are therapeutic diets an emerging additional choice in autism spectrum disorder management?},
  author={Maria Gogou and George Kolios},
  journal={World Journal of Pediatrics},
  year={2018},
  volume={14},
  pages={215-223}
}
BackgroundA nutritional background has been recognized in the pathophysiology of autism and a series of nutritional interventions have been considered as complementary therapeutic options. [] Key MethodData sourceA systematic review was conducted by two reviewers independently. Prospective clinical and preclinical studies were considered.ResultTherapeutic diets that have been used in children with autism include ketogenic and gluten/casein-free diet. We were able to identify 8 studies conducted in animal…

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References

SHOWING 1-10 OF 56 REFERENCES

The relationship of autism and gluten.

  • T. Buie
  • Medicine
    Clinical therapeutics
  • 2013

Supplement intervention associated with nutritional deficiencies in autism spectrum disorders: a systematic review

Current evidence for the use of supplements for correcting nutritional deficiencies in children with ASD and to improve the symptoms is little and more studies are needed.

Potential Therapeutic Use of the Ketogenic Diet in Autism Spectrum Disorders

Given that the mechanism of action of the KGD is not fully understood, caution should be exercised in ASD cases lacking a careful biochemical and metabolic characterization to avoid deleterious side effects or refractory outcomes.

Autism and Dietary Therapy

A child with autism and epilepsy who, after limited response to other interventions following her regression into autism, was placed on a gluten-free, casein-free diet, after which she showed marked improvement in autistic and medical symptoms.

Nutritional status of individuals with autism spectrum disorders: do we know enough?

This review article summarizes the research, focusing on the nutritional status of individuals with ASDs based on their anthropometric measurements, biomarkers, and dietary assessments, and shows inconsistent findings on the prevalence of overweight/obesity in comparison with typically growing children.

Elimination diets’ efficacy and mechanisms in attention deficit hyperactivity disorder and autism spectrum disorder

This review discusses an elimination diet as a treatment for attention deficit hyperactivity disorder and autism spectrum disorder, with a focus on the efficacy of the food additives exclusion diet, gluten-free/casein-free diet and oligoantigenic diet.

Gluten-free and casein-free diets in the therapy of autism

The findings of this study suggest additional effects of a gluten-free and casein-free diet on comorbid problems of autism such as gastrointestinal symptoms, concentration, and attention.
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