Are therapeutic diets an emerging additional choice in autism spectrum disorder management?

@article{Gogou2018AreTD,
  title={Are therapeutic diets an emerging additional choice in autism spectrum disorder management?},
  author={Maria Gogou and George Kolios},
  journal={World Journal of Pediatrics},
  year={2018},
  volume={14},
  pages={215-223}
}
BackgroundA nutritional background has been recognized in the pathophysiology of autism and a series of nutritional interventions have been considered as complementary therapeutic options. [] Key MethodData sourceA systematic review was conducted by two reviewers independently. Prospective clinical and preclinical studies were considered.ResultTherapeutic diets that have been used in children with autism include ketogenic and gluten/casein-free diet. We were able to identify 8 studies conducted in animal…
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28 Citations
Background Citations
11
Methods Citations
1
Results Citations
1

28 Citations

A Review on Nutritional and Dietary Intervention for Autism Spectrum Disorder

In this review, nutritional intervention that can be used to achieve better results in management and treatment of autism spectrum disorder is looked at.

Nutritional interventions for autism spectrum disorder.

The state of the current clinical and experimental literature on nutritional interventions for ASD, including gluten-free and casein-free, ketogenic, and specific carbohydrate diets, as well as probiotics, polyunsaturated fatty acids, and dietary supplements are summarized.

A Review of the Efficacy of the Dietary Intervention in Autism Spectrum Disorder

There is little evidence to support the use of dietary interventions for children with ASD, and further research is needed to provide up-to-date evidence.

Nutritional Supplements During Gestation and Autism Spectrum Disorder: What Do We Really Know and How Far Have We Gone?

Research based on animal models showed that choline and folic acid can have a significant impact on the expression of autism-related genes in a sex-specific manner, and the use of vitamin D and docosahexaenoic acid during gestation seem to decrease the incidence of autism in animal offspring.

The Ketogenic Diet: An Answer for Autism?

The ketogenic diet is a high fat, low carbohydrate nutritional practice intended to initiate metabolic ketosis within the body, which increases mitochondrial function and can decrease the prevalence of seizures in ASD patients.

The level of intestinal protein binding fatty acids in children with autism spectrum disorders, depending on the style of nutrition

Comparing the levels of I-FABP in children with autism spectrum disorders, depending on the adherence to a gluten-free diet found children using diet therapy were found to have significantly lower intestinal permeability.

Pharmacological, non-pharmacological and stem cell therapies for the management of autism spectrum disorders: a focus on human studies.

A Scoping Literature Review of the Relation between Nutrition and ASD Symptoms in Children

There is currently insufficient evidence for a relation between nutrition and ASD symptoms in childhood, making it impossible to provide practical nutrition guidelines; more methodological sound research is needed.

A Ketogenic Diet and the Treatment of Autism Spectrum Disorder

The neuroprotective role of a ketogenic diet in ASD is likely mediated via improvements in energy metabolism, reductions in antioxidative stress levels, control of neurotransmitters, inhibition of the mammalian target of rapamycin (mTOR) signaling pathway, and modulation of the gut microbiota.

Autism Spectrum Disorder: Neurodevelopmental Risk Factors, Biological Mechanism, and Precision Therapy

The development of multiple animal models of ASD to contribute to the disease mechanisms of ASD, as well as new studies from multiple disciplines to assess the behavioral pathology of ASD are discussed.

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