Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms.

@article{Cleeland2003AreTS,
  title={Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms.},
  author={Charles S. Cleeland and Gary J. Bennett and Robert Dantzer and Patrick M Dougherty and Adrian J. Dunn and Christina Anne Meyers and Antonius A. Miller and Richard S. Payne and James Reuben Reuben and Xin Shelley Wang and Bang-Ning Lee},
  journal={Cancer},
  year={2003},
  volume={97 11},
  pages={
          2919-25
        }
}
BACKGROUND Cancers and cancer treatments produce multiple symptoms that collectively cause a symptom burden for patients. These symptoms include pain, wasting, fatigue, cognitive impairment, anxiety, and depression, many of which co-occur. There is growing recognition that at least some of these symptoms may share common biologic mechanisms. METHODS In November 2001, basic and clinical scientists met to consider evidence for a cytokine-immunologic model of symptom expression along with… CONTINUE READING
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