Are the point-of-care diagnostics MULTIPLATE and ROTEM valid in the setting of high concentrations of heparin and its reversal with protamine?

@article{Gertler2011AreTP,
  title={Are the point-of-care diagnostics MULTIPLATE and ROTEM valid in the setting of high concentrations of heparin and its reversal with protamine?},
  author={Ralph Gertler and Gunther Wiesner and Peter Tassani-Prell and S. Braun and Klaus Daniel Martin},
  journal={Journal of cardiothoracic and vascular anesthesia},
  year={2011},
  volume={25 6},
  pages={981-6}
}
OBJECTIVES To evaluate the in vitro effects of high concentrations of heparin and its reversal with protamine on routine laboratory parameters as well as on modified thromboelastogram (ROTEM; TEM International, Munich, Germany) and impedance aggregometry (MULTIPLATE; Dynabyte, Munich, Germany). DESIGN An observational, nonrandomized in vitro study. SETTING A single-center, university hospital. PARTICIPANTS Ten healthy volunteers. INTERVENTIONS Heparinization of whole blood to levels of… CONTINUE READING
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Yentis SM: The TEG vs the ROTEM thromboelastography/thromboelastometry systems

  • GN Jackson, KJ Ashpole
  • Anaesthesia
  • 2009

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