Are the determinants of vertebral endplate changes and severe disc degeneration in the lumbar spine the same? A magnetic resonance imaging study in middle-aged male workers

@article{Kuisma2008AreTD,
  title={Are the determinants of vertebral endplate changes and severe disc degeneration in the lumbar spine the same? A magnetic resonance imaging study in middle-aged male workers},
  author={Mari Kuisma and Jaro I. Karppinen and Marianne Haapea and Jaakko L Niinim{\"a}ki and Risto Ojala and Markku Heli{\"o}vaara and Raija Korpelainen and Kaisu Marjut Kaikkonen and Simo P. Taimela and Antero Natri and Osmo Tervonen},
  journal={BMC Musculoskeletal Disorders},
  year={2008},
  volume={9},
  pages={51 - 51}
}
BACKGROUND Modic changes are bone marrow lesions visible in magnetic resonance imaging (MRI), and they are assumed to be associated with symptomatic intervertebral disc disease, especially changes located at L5-S1. Only limited information exists about the determinants of Modic changes. The objective of this study was to evaluate the determinants of vertebral endplate (Modic) changes, and whether they are similar for Modic changes and severe disc degeneration focusing on L5-S1 level. METHODS… CONTINUE READING