Are subtype differences important in HIV drug resistance?

  title={Are subtype differences important in HIV drug resistance?},
  author={Richard J Lessells and David K. Katzenstein and Tulio de Oliveira},
  journal={Current opinion in virology},
  volume={2 5},
The diversity of human immunodeficiency virus type 1 (HIV-1) has given rise to multiple subtypes and recombinant strains. The majority of research into antiretroviral agents and drug resistance has been performed on subtype B viruses, yet non-subtype B strains are responsible for 90% of global infections. Although it seems that combination antiretroviral regimens are effective against all HIV-1 subtypes, there is emerging evidence of subtype differences in drug resistance, relevant to… CONTINUE READING
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