Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?

@article{Larsen2009AreSU,
  title={Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?},
  author={Steen Bille Larsen and Ignacio Ara and Rasmus Rab{\o}l and Janet L. Andersen and R Boushel and Flemming Dela and J{\o}rn Wulff Helge},
  journal={Diabetologia},
  year={2009},
  volume={52},
  pages={1400-1408}
}
Aim/hypothesisThe aim of the study was to investigate mitochondrial function, fibre type distribution and substrate oxidation in arm and leg muscle during exercise in patients with type 2 diabetes and in obese and lean controls.MethodsIndirect calorimetry was used to calculate fat and carbohydrate oxidation during both progressive arm-cranking and leg-cycling exercises. Muscle biopsies from arm and leg were obtained. Fibre type, as well as O2 flux capacity of saponin-permeabilised muscle fibres… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

International physical activity questionnaire: 12-country reliability and validity.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL