Are rigidity and tremor two sides of the same coin in Parkinson's disease?

@article{MashhadiMalek2008AreRA,
  title={Are rigidity and tremor two sides of the same coin in Parkinson's disease?},
  author={Maysam MashhadiMalek and Farzad Towhidkhah and Shahriar Gharibzadeh and Verya Daeichin and Mohammad Ali Ahmadi-pajouh},
  journal={Computers in biology and medicine},
  year={2008},
  volume={38 11-12},
  pages={1133-9}
}
In this research, we evaluated the inter-relation of tremor and rigidity in Parkinson's disease. We included the agonist and antagonist skeletal muscle models as well as the peripheral (spinal and long-loop reflexes) and central (basal ganglia and cortex) mechanisms and present a complete model. All of our simulation is developed in SIMULINK, MATLAB 7. Our results showed that (1) increased supplementary motor area output increases the rigidity and (2) rigidity and the tremor are correlated… CONTINUE READING