Are oestrogens useful for the treatment of depression in women?

@article{Studd2009AreOU,
  title={Are oestrogens useful for the treatment of depression in women?},
  author={John W. W. Studd and Nicholas Panay},
  journal={Best practice & research. Clinical obstetrics & gynaecology},
  year={2009},
  volume={23 1},
  pages={63-71}
}
The relationship between mood changes and the menstrual cycle has been recognized for many years. Initial treatments involved removal of the ovaries to prevent fluctuation of oestradiol, but this was also associated with the long-term effects of hypo-oestrogenism such as osteoporosis or heart disease. More recently, the use of high-dose oestrogen has been explored with some success. A diagnosis of hormone-related depression is made on the history, where the problem is worse at a time of hormone… CONTINUE READING

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