Are normal healthy research volunteers psychologically healthy? A pilot investigation.

  title={Are normal healthy research volunteers psychologically healthy? A pilot investigation.},
  author={Carl L. Tishler and Glen Apseloff and Suzanne Bartholomae and Natalie Staats Reiss and Angel R Rhodes and Alpana Singh},
  journal={Experimental and clinical psychopharmacology},
  volume={15 6},
Most new drug development in Phase I clinical trials relies on the use of "normal healthy research volunteers" (NHRVs); however, little is known about the personality functioning of these volunteers. Determining whether NHRVs are similar to or different from individuals with "normal" personalities can impact participant recruitment, group assignment, and statistical interpretation of study results. This pilot study was undertaken to gain insight into the demographics, personality functioning… CONTINUE READING


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