Are neuroendocrine tumours a feature of tuberous sclerosis? A systematic review.


Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem disorder characterised by the development of multiple hamartomas in numerous organs. It is caused by mutations of two tumour suppressor genes, TSC1 on chromosome 9q34 and TSC2 on chromosome 16p13.3, which encode for hamartin and tuberin respectively. The interaction between these two… (More)
DOI: 10.1677/ERC-08-0142

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