Are macrophages in tumors good targets for novel therapeutic approaches?
@article{Alahari2015AreMI, title={Are macrophages in tumors good targets for novel therapeutic approaches?}, author={Samthosh V Alahari and S. Dong and S. Alahari}, journal={Molecules and cells}, year={2015}, volume={38 2}, pages={ 95-104 } }
The development of cancer has been an extensively researched topic over the past few decades. Although great strides have been made in cancer prevention, diagnosis, and treatment, there is still much to be learned about cancer's micro-environmental mechanisms that contribute to cancer formation and aggressiveness. Macrophages, lymphocytes which originate from monocytes, are involved in the inflammatory response and often dispersed to areas of infection to fight harmful antigens and mutated… CONTINUE READING
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- 2020
- 2
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- Biology, Medicine
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- 2017
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References
SHOWING 1-10 OF 191 REFERENCES
Identification and manipulation of tumor associated macrophages in human cancers
- Medicine
- Journal of Translational Medicine
- 2011
- 361
Tumor-associated macrophages: effectors of angiogenesis and tumor progression.
- Biology, Medicine
- Biochimica et biophysica acta
- 2009
- 292
Macrophages, innate immunity and cancer: balance, tolerance, and diversity.
- Biology, Medicine
- Current opinion in immunology
- 2010
- 1,121
Dual role of macrophages in tumor growth and angiogenesis
- Medicine, Biology
- Journal of leukocyte biology
- 2006
- 260
Obstacles and opportunities for understanding macrophage polarization
- Biology, Medicine
- Journal of leukocyte biology
- 2011
- 405
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.
- Medicine
- Blood
- 2004
- 735
- PDF
Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB.
- Biology, Medicine
- Blood
- 2009
- 172