Are low dehydroepiandrosterone sulphate levels predictive for cardiovascular diseases? A review of prospective and retrospective studies

  title={Are low dehydroepiandrosterone sulphate levels predictive for cardiovascular diseases? A review of prospective and retrospective studies},
  author={Lutgarde Thijs and Robert H. Fagard and Françoise Forette and Tim S. Nawrot and Jan A. Staessen},
  journal={Acta Cardiologica},
  pages={403 - 410}
Study objective — It has been suggested that low levels of dehydroepiandrosterone sulphate (DHEAS) are predictive for cardiovascular diseases in men.We aimed to review the available evidence from prospective cohort studies and retrospective case-control studies. Methods — We extracted summary statistics from 4 case-control studies and 8 cohort studies, and calculated the pooled relative risk associated with a 2 μmol/l increase in DHEAS. Main results — The number of subjects included in each of… 

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