Are generalized and localization-related epilepsies genetically distinct?

@article{Ottman1998AreGA,
  title={Are generalized and localization-related epilepsies genetically distinct?},
  author={Ruth Ottman and Jae Hyuk Lee and W. Allen Hauser and Neil J. Risch},
  journal={Archives of neurology},
  year={1998},
  volume={55 3},
  pages={339-44}
}
BACKGROUND Whether the genetic influences are distinct for generalized and localization-related epilepsies or whether some susceptibility genes raise the risk for both types of epilepsy is uncertain. OBJECTIVE To evaluate genetic heterogeneity in epilepsy. METHODS We used Cox proportional hazards analysis to compute rate ratios (RRs) for generalized and localization-related idiopathic or cryptogenic epilepsy in the first-degree relatives of 1498 adult probands with idiopathic or cryptogenic… CONTINUE READING

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A twin study of the epilepsies

  • SF Berkovic, RA Howell, JL Hopper, DA Hay, E. Andermann
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