Are extracellular osmolality and sodium concentration determined by Donnan effects of intracellular protein charges and of pumped sodium?

@article{Kurbel2008AreEO,
  title={Are extracellular osmolality and sodium concentration determined by Donnan effects of intracellular protein charges and of pumped sodium?},
  author={Sven Kurbel},
  journal={Journal of theoretical biology},
  year={2008},
  volume={252 4},
  pages={769-72}
}
Although we are used to attribute almost identical extracellular fluid (ECF) sodium concentrations in birds, amphibians, reptiles, and mammals to the composition of the primordial oceans in which, presumably, all life originated, this interpretation is not supported by geological data suggesting that the ocean salinity was never much lower than the present-day values, still four times higher than our plasma sodium. Here presented interpretation is that the similar ECF salt concentrations are… CONTINUE READING
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