Are cystatin C and beta 2-microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects?

@article{Filler1997AreCC,
  title={Are cystatin C and beta 2-microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects?},
  author={Guido Filler and Irene Witt and Friedrich Priem and Jochen H. H. Ehrich and Klaus Jung},
  journal={Clinical chemistry},
  year={1997},
  volume={43 6 Pt 1},
  pages={
          1077-8
        }
}
Serum creatinine is the marker most widely used to predict glomerular filtration rate (GFR). In childhood, there is age and muscle mass dependency of serum creatinine, and assessing a normal GFR accurately even with the use of body length/creatinine ratios remains difficult (1)(2). Recently, cystatin C (Cys-C), a 13-kDa protein, was found to correlate closely with GFR in adults (3)(4)(5). β2-Microglobulin (β2-MG) serum concentrations also correlate with GFR, and have been shown to be age… CONTINUE READING

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