Are cross-regulatory interactions between homoeotic genes functionally significant?

  title={Are cross-regulatory interactions between homoeotic genes functionally significant?},
  author={Acaimo Gonz{\'a}lez-Reyes and N. Urquia and W. J. Gehring and Gary Struhl and Gin{\'e}s Morata},
THE first instar larva of Drosophila consists of a chain of segments or parasegments1 in which the morphological pattern characteristic of each metaniere is determined by the homoeotic genes2–4, which are active in overlapping domains and are known to interact among themselves5–9. The interactions occur at the level of transcription and allow some homoeotic genes to control the patterns and levels of expression of others. The best known among them are the down-regulation of Antennapedia (Antp… CONTINUE READING

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