Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide?

@article{Dudek2013AreAP,
  title={Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide?},
  author={Magdalena B Dudek and Anna Bilska-Wilkosz and Joanna Knutelska and Szczepan Mogilski and Marek Bednarski and Małgorzata Zygmunt and Małgorzata B Iciek and Jacek Sapa and Dominik Bugajski and Barbara Filipek and Lidia B Włodek},
  journal={Pharmacological reports : PR},
  year={2013},
  volume={65 4},
  pages={
          1018-24
        }
}
BACKGROUND Lipoic acid (LA) was shown to possess anti-inflammatory properties. In this study, we present evidence supporting the hypothesis that the anti-inflammatory properties of LA are associated with the formation of hydrogen sulfide (H2S). METHODS The study was conducted on male albino Swiss mice. The animals were treated with carrageenan by subcutaneous (sc) injection into the right hind paw to induce acute inflammation. Animals were treated intraperitoneally (ip) with LA (30, 50 and… CONTINUE READING
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