Corpus ID: 41247420

Are all "cytoprotective" drugs gastroprotective?

  title={Are all "cytoprotective" drugs gastroprotective?},
  author={Kl{\'a}ra Gyires},
  journal={Acta physiologica Hungarica},
  volume={80 1-4},
  • Klára Gyires
  • Published 1992
  • Medicine
  • Acta physiologica Hungarica
  • The effect of three--structurally different--groups of compounds was compared against gastric mucosal damages induced by ethanol or prostaglandin (PG) synthesis inhibitors, as well as against carrageenan-induced inflammation. All the compounds studied--SH-compounds (cysteamine, 2,3-dimercaptosuccinic acid, D,L-penicillamine), SH-blocking N-ethylmaleimide (NEM) and morphine-exerted dose-dependent inhibition on carrageenan edema test and against ethanol-induced gastric damage. Mucosal lesions… CONTINUE READING