Are There Progressive Brain Changes in Schizophrenia? A Meta-Analysis of Structural Magnetic Resonance Imaging Studies

@article{Olabi2011AreTP,
  title={Are There Progressive Brain Changes in Schizophrenia? A Meta-Analysis of Structural Magnetic Resonance Imaging Studies},
  author={Bayanne Olabi and Ian Ellison-Wright and Andrew M. McIntosh and Stephen J. Wood and Stephen M Lawrie},
  journal={Biological Psychiatry},
  year={2011},
  volume={70},
  pages={88-96}
}
BACKGROUND It is well established that schizophrenia is associated with structural brain abnormalities, but whether these are static or progress over time remains controversial. METHODS A systematic review of longitudinal volumetric studies using region-of-interest structural magnetic resonance imaging in patients with schizophrenia and healthy control subjects. The percentage change in volume between scans for each brain region of interest was obtained, and data were combined using random… CONTINUE READING
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