Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?

@article{Peigneux2004AreSM,
  title={Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?},
  author={P. Peigneux and S. Laureys and S. Fuchs and F. Collette and F. Perrin and J. Reggers and C. Phillips and C. Degueldre and G. D. Fiore and Jo{\"e}l J Aerts and A. Luxen and P. Maquet},
  journal={Neuron},
  year={2004},
  volume={44},
  pages={535-545}
}
  • P. Peigneux, S. Laureys, +9 authors P. Maquet
  • Published 2004
  • Psychology, Medicine
  • Neuron
  • In rats, the firing sequences observed in hippocampal ensembles during spatial learning are replayed during subsequent sleep, suggesting a role for posttraining sleep periods in the offline processing of spatial memories. Here, using regional cerebral blood flow measurements, we show that, in humans, hippocampal areas that are activated during route learning in a virtual town are likewise activated during subsequent slow wave sleep. Most importantly, we found that the amount of hippocampal… CONTINUE READING

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