Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?

@article{Peigneux2004AreSM,
  title={Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?},
  author={P. Peigneux and Steven Laureys and S. Fuchs and F. Collette and F. Perrin and J. Reggers and C. Phillips and C. Degueldre and G. D. Fiore and J. Aerts and A. Luxen and P. Maquet},
  journal={Neuron},
  year={2004},
  volume={44},
  pages={535-545}
}
In rats, the firing sequences observed in hippocampal ensembles during spatial learning are replayed during subsequent sleep, suggesting a role for posttraining sleep periods in the offline processing of spatial memories. Here, using regional cerebral blood flow measurements, we show that, in humans, hippocampal areas that are activated during route learning in a virtual town are likewise activated during subsequent slow wave sleep. Most importantly, we found that the amount of hippocampal… Expand

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  • P. Orban, G. Rauchs, +4 authors P. Peigneux
  • Psychology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2006
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