Are Protein Domains Modules of Lateral Genetic Transfer?

@article{Chan2009ArePD,
  title={Are Protein Domains Modules of Lateral Genetic Transfer?},
  author={Cheong Xin Chan and Aaron E. Darling and Robert G. Beiko and Mark A. Ragan},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={2124 - 2128}
}
BACKGROUND In prokaryotes and some eukaryotes, genetic material can be transferred laterally among unrelated lineages and recombined into new host genomes, providing metabolic and physiological novelty. Although the process is usually framed in terms of gene sharing (e.g. lateral gene transfer, LGT), there is little reason to imagine that the units of transfer and recombination correspond to entire, intact genes. Proteins often consist of one or more spatially compact structural regions… CONTINUE READING
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