Are Dopamine Receptor Agonists Neuroprotective in Parkinson’s Disease?

@article{Le2001AreDR,
  title={Are Dopamine Receptor Agonists Neuroprotective in Parkinson’s Disease?},
  author={Wei-dong Le and Joseph Jankovic},
  journal={Drugs & Aging},
  year={2001},
  volume={18},
  pages={389-396}
}
Dopamine receptor agonists are playing an increasingly important role in the treatment of not only patients with advanced Parkinson’s disease and those with levodopa-induced motor fluctuations, but also in the early treatment of the disease. This shift has been largely due to the demonstrated levodopa-sparing effect of dopamine agonists and their putative neuroprotective effect, with evidence for the latter being based largely on experimental in vitro and in vivo studies. In this article we… CONTINUE READING

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