Are Cardiovascular Benefits in Statin Lipid Effects Dependent on Baseline Lipid Levels?

@article{Ferdinand2011AreCB,
  title={Are Cardiovascular Benefits in Statin Lipid Effects Dependent on Baseline Lipid Levels?},
  author={Keith C Ferdinand},
  journal={Current Atherosclerosis Reports},
  year={2011},
  volume={13},
  pages={64-72}
}
  • Keith C Ferdinand
  • Published 2011
  • Medicine
  • Current Atherosclerosis Reports
  • Statins reduce coronary heart disease (CHD) morbidity and mortality over a wide range of patients. The Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) in subjects with elevated C-reactive protein, without vascular disease and below average low-density lipoprotein cholesterol (LDL-C) showed a 50% reduction in LDL-C with 20 mg/d of rosuvastatin and a reduction in cardiovascular events (hazard ratio 0.56 [95% CI, 0.46–0.69]; P < 0.00001… CONTINUE READING

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