Are Antidepressant Drugs That Combine Serotonergic and Noradrenergic Mechanisms of Action More Effective Than the Selective Serotonin Reuptake Inhibitors in Treating Major Depressive Disorder? A Meta-analysis of Studies of Newer Agents

@article{Papakostas2007AreAD,
  title={Are Antidepressant Drugs That Combine Serotonergic and Noradrenergic Mechanisms of Action More Effective Than the Selective Serotonin Reuptake Inhibitors in Treating Major Depressive Disorder? A Meta-analysis of Studies of Newer Agents},
  author={G. Papakostas and M. Thase and M. Fava and J. Nelson and R. Shelton},
  journal={Biological Psychiatry},
  year={2007},
  volume={62},
  pages={1217-1227}
}
  • G. Papakostas, M. Thase, +2 authors R. Shelton
  • Published 2007
  • Psychology, Medicine
  • Biological Psychiatry
  • BACKGROUND Recent studies suggest that the treatment of major depressive disorder (MDD) with newer antidepressant drugs that simultaneously enhance norepinephrine and serotonin neurotransmission might result in higher response and remission rates than the selective serotonin reuptake inhibitors (SSRIs). The goal of our work was to compare response rates among patients with MDD treated with either of these two broad categories of antidepressant drugs. METHODS Medline/Pubmed, EMBase, clinical… CONTINUE READING
    265 Citations
    Duloxetine in the acute and continuation treatment of major depressive disorder
    • 2

    References

    SHOWING 1-10 OF 130 REFERENCES
    A Metaanalysis of Clinical Trials Comparing Moclobemide with Selective Serotonin Reuptake Inhibitors for the Treatment of Major Depressive Disorder
    • G. Papakostas, M. Fava
    • Psychology, Medicine
    • Canadian journal of psychiatry. Revue canadienne de psychiatrie
    • 2006
    • 41
    • PDF
    Pharmacogenetics of antidepressant medication intolerance.
    • 251
    • PDF