Ardipusilloside inhibits survival, invasion and metastasis of human hepatocellular carcinoma cells.

@article{Lou2012ArdipusillosideIS,
  title={Ardipusilloside inhibits survival, invasion and metastasis of human hepatocellular carcinoma cells.},
  author={Lianqing Lou and Weiwei Ye and Yongxin Chen and Shuang Wu and Linzheng Jin and Jinke He and Xingfei Tao and Jinghong Zhu and Xiangyi Chen and An-Mei Deng and Jinhe Wang},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2012},
  volume={19 7},
  pages={603-8}
}
ETHNOPHARMACOLOGICAL RELEVANCE Ardipusilloside I is a triterpene-saponin isolated from the Traditional Chinese Medicine Ardisia pusilla A. DC. Its effects and mechanism on invasion and metastasis of liver cancer cells are unclear. MATERIALS AND METHODS The human hepatocellular carcinoma cell line HepG2 and SMMC-7721 cells were treated with different doses of Ardipusilloside I. Cellular survival, in vitro migration and invasion were evaluated. In vivo metastatic abilities of the HCC cells were… CONTINUE READING