Ardeparin sodium for extended out-of-hospital prophylaxis against venous thromboembolism after total hip or knee replacement. A randomized, double-blind, placebo-controlled trial.

@article{Heit2000ArdeparinSF,
  title={Ardeparin sodium for extended out-of-hospital prophylaxis against venous thromboembolism after total hip or knee replacement. A randomized, double-blind, placebo-controlled trial.},
  author={John A Heit and Charles Gregory Elliott and A A Trowbridge and B F Morrey and M Gent and J Hirsh},
  journal={Annals of internal medicine},
  year={2000},
  volume={132 11},
  pages={853-61}
}
The optimal duration of prophylaxis against venous thromboembolism after elective total hip or knee replacement is uncertain. In previous clinical trials, prophylaxis was given until hospital discharge and ranged from 7 to 14 days. However, the prevalence of asymptomatic deep venous thrombosis at hospital discharge was still approximately 15% for patients who had total hip replacement and 30% for those who had total knee replacement (1). Because most patients are now discharged by the third or… CONTINUE READING
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