Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer.

@article{Bennett1991ArchivalAO,
  title={Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer.},
  author={William P. Bennett and Monica C. Hollstein and Aiqing He and Sheng Mei Zhu and James H. Resau and Benjamin F. Trump and Robert A. Metcalf and Judith A. Welsh and Carol A. Midgley and David Philip Lane},
  journal={Oncogene},
  year={1991},
  volume={6 10},
  pages={1779-84}
}
A strategy and methods for archival analysis of genetic and protein alterations in the p53 tumor-suppressor gene are presented. The tumor series includes 43 paraffin-embedded esophageal carcinomas from two high-incidence regions in the People's Republic of China. More than half contained elevated p53 protein levels which were detected by a high-titer… CONTINUE READING