Architecture of the yeast small subunit processome

  title={Architecture of the yeast small subunit processome},
  author={Malik Chaker-Margot and Jonas Barandun and Mirjam Hunziker and Sebastian Klinge},
The small subunit (SSU) processome, a large ribonucleoprotein particle, organizes the assembly of the eukaryotic small ribosomal subunit by coordinating the folding, cleavage, and modification of nascent pre–ribosomal RNA (rRNA). Here, we present the cryo–electron microscopy structure of the yeast SSU processome at 5.1-angstrom resolution. The structure reveals how large ribosome biogenesis complexes assist the 5′ external transcribed spacer and U3 small nucleolar RNA in providing an… CONTINUE READING
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