Architecture and the extracellular matrix: the still unappreciated components of the adipose tissue.

@article{Divoux2011ArchitectureAT,
  title={Architecture and the extracellular matrix: the still unappreciated components of the adipose tissue.},
  author={Adeline Divoux and Karine Cl{\'e}ment},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  year={2011},
  volume={12 5},
  pages={e494-503}
}
Fibrosis is usually characterized by the modification of both the amount and composition of a wide panel of extracellular matrix (ECM) proteins. In the liver, pancreas, kidney and lung the accumulation of fibrosis disrupts cellular processes and appears detrimental for organ function. This review highlights the available evidence supporting an important ECM remodelling in adipose tissue (AT) and, in particular, during the development of obesity. The modifications and occurrence of new adipose… CONTINUE READING
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