Architecture and cell types of the adult subventricular zone: in search of the stem cells.

@article{GarcaVerdugo1998ArchitectureAC,
  title={Architecture and cell types of the adult subventricular zone: in search of the stem cells.},
  author={Jose Manuel Garc{\'i}a-Verdugo and Fiona Doetsch and Hynek Wichterle and Daniel A. Lim and Arturo Alvarez-Buylla},
  journal={Journal of neurobiology},
  year={1998},
  volume={36 2},
  pages={234-48}
}
Neural stem cells are maintained in the subventricular zone (SVZ) of the adult mammalian brain. Here, we review the cellular organization of this germinal layer and propose lineage relationships of the three main cell types found in this area. The majority of cells in the adult SVZ are migrating neuroblasts (type A cells) that continue to proliferate. These cells form an extensive network of tangentially oriented pathways throughout the lateral wall of the lateral ventricle. Type A cells move… CONTINUE READING

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