Archaebacterial elongation factor Tu insensitive to pulvomycin and kirromycin.

@article{Cammarano1982ArchaebacterialEF,
  title={Archaebacterial elongation factor Tu insensitive to pulvomycin and kirromycin.},
  author={Piero Cammarano and Angela Teichner and Gianni Chinali and Paola Londei and Mario de Rosa and Agata Gambacorta and Barbara Nicolaus},
  journal={FEBS letters},
  year={1982},
  volume={148 2},
  pages={255-9}
}
A spermine-dependent, polyphenylalanine-synthesizing cell-free system having an optimum activity at 75-85 degrees C, has been developed from the extremely thermoacidophilic archaebacterium Caldariella acidophila. The C. acidophila system is totally insensitive to the EF-Tu targeted antibiotics pulvomycin (at 40 degrees C) and kirromycin (at 47-72 degrees C… CONTINUE READING