Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome.

@article{Puehler1989ArchaebacterialDR,
  title={Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome.},
  author={Gabriela Puehler and Henrik Leffers and Felix Gropp and Peter Elmer Palm and Hans Peter Klenk and Friedrich Lottspeich and Roger A. Garrett and W. Zillig},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 12},
  pages={
          4569-73
        }
}
Genes for DNA-dependent RNA polymerase components B, A, and C from the archaebacterium Sulfolobus acidocaldarius and for components B", B', A, and C from the archaebacterium Halobacterium halobium were cloned and sequenced. They are organized in gene clusters in the order above, which corresponds to the order of the homologous rpoB and rpoC genes in the corresponding operon of the Escherichia coli genome. Derived amino acid sequences of archaebacterial components A and C were aligned with each… CONTINUE READING
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