Archaeal Ribosomes

  title={Archaeal Ribosomes},
  author={Paola Londei},

A Twist to the Kirby-Bauer Disk Diffusion Susceptibility Test: an Accessible Laboratory Experiment Comparing Haloferax volcanii and Escherichia coli Antibiotic Susceptibility to Highlight the Unique Cell Biology of Archaea

Two versions of this experiment are developed, one designed for an undergraduate laboratory curriculum and the second, limited to H. volcanii, that high school students can perform in their classrooms, making the experiment low-cost and safe for use in the high school setting.

Macrobiont: Cradle for the Origin of Life and Creation of a Biosphere

Comparison of ponds with other macrobionts allows a conclusion that more than one possible macrobIONt locale could enable an OoL, and Pond size-sensitivities for several figures of merit are mathematically formulated, leading to the expectation that the optimum pond size for the OoL is intermediate, but biased toward smaller sizes.



Protein content of minimal and ancestral ribosome.

This work relates ribosomal gene content in completely sequenced genomes to Ribosomal subunit structure and approximate the protein components of the putative minimal ribosome and the ribosomes of the Last Universal Common Ancestor of Life.

Ribosomes and translation.

Biochemical and genetic approaches have identified specific functional interactions involving conserved nucleotides in 16S and 23S rRNA and promise to yield an unprecedented view of the mechanism of translation in the coming years.

Ribosomal RNA introns in archaea and evidence for RNA conformational changes associated with splicing.

  • J. KjemsR. Garrett
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1991
The single 23S rRNA gene of the archaeon Staphylothermus marinus exhibits two introns which, at the RNA level, are located in highly conserved regions of domains IV and V, and parts of this structural feature that are essential for cleavage are defined using a phylogenetic sequence comparison approach.

Evidence that eukaryotes and eocyte prokaryotes are immediate relatives.

The eocytes are the closest surviving relatives (sister taxon) of the eukaryotes, and the related (paralogous) genes encoding elongation factor EF-2 and initiation factor IF-2 also lacked the 11-amino acid insert.

Mapping evolution with ribosome structure: intralineage constancy and interlineage variation.

The intralineage conservation of ribosomal three-dimensional structure is interpreted as forming a phylogenetic basis for regarding archaebacteria, eubacteria, and eukaryotes as primitive lines.

Ribonucleoproteins in Archaeal Pre-rRNA Processing and Modification

This paper will introduce archaeal rRNA gene organization and pre-rRNA processing, with a particular focus on the discovery of the archaealing sRNP components, their functions in nucleotide modification, and their structures.

Small nucleolar RNA‐guided post‐transcriptional modification of cellular RNAs

  • T. Kiss
  • Biology, Chemistry
    The EMBO journal
  • 2001
Post‐transcriptional modification of individual ribonucleotides, namely deamination of adenosines and cytidines, can also change the readout of mRNAs, and lack of ribosomal pseudouridines can reduce the growth rate or confer a selective disadvantage when it is competed against wild‐type ribosomes.

Small Nucleolar RNAs Guide Ribosomal RNA Methylation

How these newly described small nucleolar RNAs control the site of methylation of the ribosomal RNA (rRNA) is explained and the possible role of this rRNA modification is discussed.

Particle weights and protein composition of the ribosomal subunits of the extremely thermoacidophilic archaebacterium Caldariella acidophila.

It is concluded that the heavier-than-eubacterial mass of the C. acidophila ribosomes resides principally in their smaller subunits.