Archaeal DNA polymerase D but not DNA polymerase B is required for genome replication in Thermococcus kodakarensis.

@article{uboov2013ArchaealDP,
  title={Archaeal DNA polymerase D but not DNA polymerase B is required for genome replication in Thermococcus kodakarensis.},
  author={Ľubom{\'i}ra {\vC}uboňov{\'a} and Tomas T. Richardson and Brett W Burkhart and Zvi Kelman and Bernard A. Connolly and John N Reeve and Thomas J. Santangelo},
  journal={Journal of bacteriology},
  year={2013},
  volume={195 10},
  pages={2322-8}
}
Three evolutionarily distinct families of replicative DNA polymerases, designated polymerase B (Pol B), Pol C, and Pol D, have been identified. Members of the Pol B family are present in all three domains of life, whereas Pol C exists only in Bacteria and Pol D exists only in Archaea. Pol B enzymes replicate eukaryotic chromosomal DNA, and as members of the Pol B family are present in all Archaea, it has been assumed that Pol B enzymes also replicate archaeal genomes. Here we report the… CONTINUE READING
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