Arachidonic acid prevents fatty liver induced by conjugated linoleic acid in mice.

@article{Oikawa2009ArachidonicAP,
  title={Arachidonic acid prevents fatty liver induced by conjugated linoleic acid in mice.},
  author={Daichi Oikawa and Shoichiro Tsuyama and Yoriko Akimoto and Yurika Mizobe and Mitsuhiro Furuse},
  journal={The British journal of nutrition},
  year={2009},
  volume={101 10},
  pages={
          1558-63
        }
}
Conjugated linoleic acid (CLA) has anti-obesity effects, but induces fatty liver in mice. The present study investigated whether co-administration of arachidonic acid (ARA) attenuates fat accumulation in the mouse liver induced by CLA. Male mice (8 weeks old) were given diets with either no addition of dietary fat (control), 3 % linoleic acid (LA), 3 % CLA, 3 % CLA+1 % ARA, or 3 % CLA+2 % ARA for 4 weeks. The perirenal fat weight in ARA-treated groups decreased similarly as with CLA alone, when… CONTINUE READING

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