Arachidonic acid preserves hippocampal neuron membrane fluidity in senescent rats

@article{Fukaya2007ArachidonicAP,
  title={Arachidonic acid preserves hippocampal neuron membrane fluidity in senescent rats},
  author={Taisuke Fukaya and Takumi Gondaira and Yasuto Kashiyae and Susumu Kotani and Yoshiyuki Ishikura and Shigeaki Fujikawa and Yoshinobu Kiso and Manabu Sakakibara},
  journal={Neurobiology of Aging},
  year={2007},
  volume={28},
  pages={1179-1186}
}
Arachidonic or Docosahexaenoic Acid Diet Prevents Memory Impairment in Tg2576 Mice.
TLDR
It is reported here that 4 months of treatment of Tg2576 mice with an arachidonic acid (ARA)- or a docosahexaenoic acid (DHA)-containing (ARA+ or DHA+) diet prevented memory impairment at 13 months of age, and suggest that not only the DHA+ diet, but also the ARA+ diet could prevent cognitive dysfunction in Tg 2576 mice through the alteration of AβPP processing.
Expression of fatty acid‐binding proteins in adult hippocampal neurogenic niche of postischemic monkeys
TLDR
The expression of FABP 3, 5, and 7 in the SGZ supports a role of astrocyte‐ and/or neural progenitor‐derived FABPs as components of the molecular machine regulating the progenitors cell niche in the adult primate brain.
Inhibition of phospholipase A2 in rat brain modifies different membrane fluidity parameters in opposite ways
Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle
TLDR
The present review analyzes the neuroprotective role of DHA and AA in the extreme stages of life, emphasizing the importance of these LCPUFA during the first year of life and in the developing/prevention of neurodegenerative diseases associated with aging.
Effects of PUFA, Especially Arachidonic Acid on the Aged Brain Function and It’s Mechanisms
TLDR
The effects of PUFA on cognitive function revealed by the results of animal experiments from the view point of behavior, electrophysiology, opto-physiology, membrane-biophysics, immunohistochemistry, and biochemistry are summarized in this review.
Arachidonic Acid Drives Postnatal Neurogenesis and Elicits a Beneficial Effect on Prepulse Inhibition, a Biological Trait of Psychiatric Illnesses
TLDR
The potential benefit of ARA in ameliorating PPI deficits relevant to psychiatric disorders is suggested and the effect may be correlated with augmented postnatal neurogenesis.
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TLDR
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