Arachidonic acid potentiates currents through Ca2+-permeable AMPA receptors by interacting with a CaMKII pathway.

@article{Nishizaki1999ArachidonicAP,
  title={Arachidonic acid potentiates currents through Ca2+-permeable AMPA receptors by interacting with a CaMKII pathway.},
  author={Takafumi Nishizaki and Tadasu Matsuoka and Tamotsu Nomura and Grigori Enikolopov and Katumi Sumikawa},
  journal={Brain research. Molecular brain research},
  year={1999},
  volume={67 1},
  pages={184-9}
}
The present study investigated the effect of arachidonic acid on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, presumably heteromeric receptors formed of GluR1, GluR2, and GluR3, expressed in Xenopus oocytes. Arachidonic acid (10 microM) potentiated currents through receptors expressing GluR1 and 3 (GluR1,3) to 170% of basal… CONTINUE READING