Arachidonic acid metabolism.

  title={Arachidonic acid metabolism.},
  author={J C Mcgiff},
  journal={Preventive medicine},
  volume={16 4},
Arachidonic acid metabolites can act as tumor promoters and can affect growth and metastases of tumors in three ways: (a) Prostacyclin inhibits and thromboxane facilitates platelet-tumor cell interactions and, thereby, tumor cell invasiveness; (b) the cytoprotective action of prostaglandins contributes to epithelial cell integrity and influences tissue response to tumor-promoting agents; and (c) lipoxygenase products may act as tumor promoters. 
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