Arabidopsis thaliana ALG3 mutant synthesizes immature oligosaccharides in the ER and accumulates unique N-glycans.

@article{Kajiura2010ArabidopsisTA,
  title={Arabidopsis thaliana ALG3 mutant synthesizes immature oligosaccharides in the ER and accumulates unique N-glycans.},
  author={Hiroyuki Kajiura and Tatsuji Seki and Kazuhito Fujiyama},
  journal={Glycobiology},
  year={2010},
  volume={20 6},
  pages={736-51}
}
The core oligosaccharide Glc(3)Man(9)GlcNAc(2) is assembled by a series of membrane-bound glycosyltransferases as the lipid carrier dolichylpyrophosphate-linked glycan in the endoplasmic reticulum (ER). The first step of this assembly pathway on the ER luminal side is mediated by ALG3 (asparagine-linked glycosylation 3), which is a highly conserved reaction among eukaryotic cells. Complementary genetics compared with Saccharomyces cerevisiae ALG gene families and bioinformatic approaches have… CONTINUE READING

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2008.Deletionof theTbALG3genedemonstrates site-specificN-glycosylation and N-glycan processing in Trypanosoma brucei

  • S Manthri, M Lucia, S Güther, L Izquierdo, A Acosta-Serrano, MAJ. Ferguson
  • Glycobiology
  • 2008
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