Arabidopsis phytochelatin synthase 1, but not phytochelatin synthesis, functions in extracellular defense against multiple fungal pathogens

@article{Hmaty2019ArabidopsisPS,
  title={Arabidopsis phytochelatin synthase 1, but not phytochelatin synthesis, functions in extracellular defense against multiple fungal pathogens},
  author={Kian H{\'e}maty and Melisa Lim and Candice Cherk and Paweł Bednarek and Mariola Piślewska‐Bednarek and Clara S{\'a}nchez-Rodr{\'i}guez and Monica Stein and Ren{\'e} Fuchs and Christine Klapprodt and Volker Lipka and Antonio Molina and Erwin Grill and Paul Schulze-Lefert and Shauna C Somerville},
  journal={bioRxiv},
  year={2019}
}
Phytochelatin synthase (PCS) is a key component of heavy metal detoxification in plants. PCS catalyzes both the synthesis of the peptide phytochelatin from glutathione as well as the degradation of glutathione conjugates via peptidase activity. Here, we describe a hitherto uncharacterized role for PCS in disease resistance against plant pathogenic fungi. The pen4 mutant, which is allelic to cadmium insensitive 1 (cad1/pcs1) mutants, was recovered from a screen for Arabidopsis mutants with… Expand
3 Citations
De novo indol-3-ylmethyl glucosinolate biosynthesis, and not long-distance transport, contributes to defence of Arabidopsis against powdery mildew.
TLDR
It is concluded that epidermal de novo synthesis of indol-3-ylmethyl glucosinolate contributes to CYP81F2-mediated broad-spectrum antifungal resistance and that adapted powdery mildews may target this process. Expand
De novo indol-3-ylmethyl glucosinolate biosynthesis, and not long-distance transport, contributes to defence of Arabidopsis against powdery mildew
Powdery mildew is a fungal disease that affects a wide range of plants and reduces crop yield worldwide. As obligate biotrophs, powdery mildew fungi manipulate living host cells to suppress defenceExpand
bak1-5 mutation uncouples tryptophan-dependent and independent postinvasive immune pathways triggered in Arabidopsis by multiple fungal pathogens
TLDR
CYP71A12 and CYP71A13 are critical for Arabidopsis’ postinvasive resistance toward both the necrotrophic Alternaria brassicicola and the adapted hemibiotrophic C. higginsianum fungi, and the disruption of intact pattern recognition receptor complex caused by bak1–5 mutation significantly reduced postin invasive resistance. Expand

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TLDR
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TLDR
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