Arabidopsis chromatin-associated HMGA and HMGB use different nuclear targeting signals and display highly dynamic localization within the nucleus.

@article{Launholt2006ArabidopsisCH,
  title={Arabidopsis chromatin-associated HMGA and HMGB use different nuclear targeting signals and display highly dynamic localization within the nucleus.},
  author={Dorte Launholt and Thomas Merkle and Andreas Houben and Alexander Schulz and Klaus D Grasser},
  journal={The Plant cell},
  year={2006},
  volume={18 11},
  pages={2904-18}
}
In plants, the chromatin-associated high mobility group (HMG) proteins occur in two subfamilies termed HMGA and HMGB. The HMGA proteins are characterized by the presence of four AT-hook DNA binding motifs, and the HMGB proteins contain an HMG box DNA binding domain. As architectural factors, the HMG proteins appear to be involved in the regulation of transcription and other DNA-dependent processes. We have examined the subcellular localization of Arabidopsis thaliana HMGA, HMGB1, and HMGB5… CONTINUE READING