Arabidopsis chloroplastic glutaredoxin C5 as a model to explore molecular determinants for iron-sulfur cluster binding into glutaredoxins.

@article{Couturier2011ArabidopsisCG,
  title={Arabidopsis chloroplastic glutaredoxin C5 as a model to explore molecular determinants for iron-sulfur cluster binding into glutaredoxins.},
  author={J{\'e}r{\'e}my Couturier and Elke Str{\"o}her and Angela-Nadia Albetel and Thomas Roret and Meenakumari Muthuramalingam and Lionel Tarrago and Thorsten Seidel and Pascale Tsan and Jean-Pierre Jacquot and Michael K. Johnson and K A Dietz and Claude Didierjean and Nicolas Rouhier},
  journal={The Journal of biological chemistry},
  year={2011},
  volume={286 31},
  pages={27515-27}
}
Unlike thioredoxins, glutaredoxins are involved in iron-sulfur cluster assembly and in reduction of specific disulfides (i.e. protein-glutathione adducts), and thus they are also important redox regulators of chloroplast metabolism. Using GFP fusion, AtGrxC5 isoform, present exclusively in Brassicaceae, was shown to be localized in chloroplasts. A comparison of the biochemical, structural, and spectroscopic properties of Arabidopsis GrxC5 (WCSYC active site) with poplar GrxS12 (WCSYS active… CONTINUE READING