Arabidopsis UVH6, a homolog of human XPD and yeast RAD3 DNA repair genes, functions in DNA repair and is essential for plant growth.

@article{Liu2003ArabidopsisUA,
  title={Arabidopsis UVH6, a homolog of human XPD and yeast RAD3 DNA repair genes, functions in DNA repair and is essential for plant growth.},
  author={Zongrang Liu and S W Hong and Mindy M Escobar and Elizabeth Vierling and David Mitchell and David W. Mount and J. D. Hall},
  journal={Plant physiology},
  year={2003},
  volume={132 3},
  pages={1405-14}
}
To evaluate the genetic control of stress responses in Arabidopsis, we have analyzed a mutant (uvh6-1) that exhibits increased sensitivity to UV light, a yellow-green leaf coloration, and mild growth defects. We have mapped the uvh6-1 locus to chromosome I and have identified a candidate gene, AtXPD, within the corresponding region. This gene shows sequence similarity to the human (Homo sapiens) XPD and yeast (Saccharomyces cerevisiae) RAD3 genes required for nucleotide excision repair. We… CONTINUE READING