Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity.

@article{Feys2005ArabidopsisSG,
  title={Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity.},
  author={Bart J. Feys and Marcel Wiermer and Riyaz Ahmed Bhat and Lisa J. Moisan and Nieves Medina-Escobar and Christina Neu and Adriana Cabral and Jane E Parker},
  journal={The Plant cell},
  year={2005},
  volume={17 9},
  pages={2601-13}
}
Plant innate immunity against invasive biotrophic pathogens depends on the intracellular defense regulator ENHANCED DISEASE SUSCEPTIBILITY1 (EDS1). We show here that Arabidopsis thaliana EDS1 interacts in vivo with another protein, SENESCENCE-ASSOCIATED GENE101 (SAG101), discovered through a proteomic approach to identify new EDS1 pathway components. Together with PHYTOALEXIN-DEFICIENT4 (PAD4), a known EDS1 interactor, SAG101 contributes intrinsic and indispensable signaling activity to EDS1… CONTINUE READING
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