Arabidopsis RETINOBLASTOMA-RELATED is required for stem cell maintenance, cell differentiation, and lateral organ production.

@article{Borghi2010ArabidopsisRI,
  title={Arabidopsis RETINOBLASTOMA-RELATED is required for stem cell maintenance, cell differentiation, and lateral organ production.},
  author={Lorenzo Borghi and Ruben Gutzat and Johannes F{\"u}tterer and Yec'han Laizet and Lars Hennig and Wilhelm Gruissem},
  journal={The Plant cell},
  year={2010},
  volume={22 6},
  pages={1792-811}
}
Several genes involved in the regulation of postembryonic organ initiation and growth have been identified. However, it remains largely unclear how developmental cues connect to the cell cycle. RETINOBLASTOMA RELATED (RBR) is a plant homolog of the tumor suppressor Retinoblastoma (pRb), which is a key regulator of the cell cycle. Using inducible RNA interference (RNAi) against Arabidopsis thaliana RBR (RBRi), we reduced RBR expression levels at different stages of plant development. Conditional… CONTINUE READING
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